Scientific Literature

Title Source Description
Comparative Effectiveness of Dried Plasma HIV-1 Viral Load Testing in Brazil using ViveST for Sample Collection Journal of Clinical Virology, December 2010, p. 245-248. Assesses the reproducibility of ViveST and compares HIV viral load results from ViveST to those from frozen plasma.
Comparative Effectiveness of Dried Plasma HBV Viral Load Testing in Three Different Viral Load Commercial Platforms Using ViveST for Sample Collection In press. Assesses the reproducibility of ViveST and compares HBV viral load results from ViveST to those from frozen plasma.
Dried-Plasma Transport Using a Novel Matrix Collection System for Human Immunodefiency Virus and Hepatitis C Virus Virologic Testing Journal of Clinical Microbiology, May 2009, p. 1491-1496 A comparison of ViveST (previously SampleTanker) against frozen plasma with multiple analytes for both shipping and storage.
Comparison of Hepatitis Quantitative and Qualitative Methods Using ViveST Sample Transportation Matrix vs Frozen Plasma 26th Clinical Virology Symposium; April 25-28, 2010; Daytona Beach, FL, USA An evaluation of ViveST for plasma samples containing three different hepatitis virus; HBV, HCV and HDV.
Cost Effectiveness of International Shipment of Dried Plasma for HIV Resistance Testing IAS 2009; July 19-22, 2009; Cape Town, South Africa Compares fresh-frozen plasma samples to ViveST for HIV genotyping. The samples are shipped internationally from Israel and the UK, and nationally from California to Georgia.
Evaluation of ViveST®for Collection, Storage and Transport of Dried Plasma From a Resource-Limited Setting (R-LS) to a Resource-Rich Setting (R-RS) for HIV-1 Genotypic Analysis 4th International Workshop on HIV Transmission-Principles of Intervention; July 17-18, 2009; Cape Town, South Africa Utilizes ViveST for transport of HIV genotypes utilizing low-tech methods.
HIV Diversity and Drug Resistance in Western Kenya From Plasma and Non-Plasma Genotyping 4th International Workshop on HIV Transmission-Principles of Intervention; July 17-18, 2009; Cape Town, South Africa Examines HIV diversity and drug resistance in western Kenya using frozen plasma and ViveST.
Use of Plasma, Dried Plasma, and Dried Blood With Automated Sample Preparation and Detection for TRUGENE® HIV-1 Integrase Genotyping Assay 7th European HIV Drug Resistance Workshop, March 25-27, 2009; Stockholm, Sweden Compares plasma, dried plasma (ViveST), and dried blood spots genotypic analysis utilizing a prototype TRUGENE CLIP module for the TRUGENE HIV-1 integrase assay.
Development of a Genotyping Assay for HIV-1 Integrase Compatible With Globally Available IVD Platforms 20th International Congress of Clinical Chemistry and Laboratory Medicine, September 28th - October 2, 2008; Fortaleza, Brazil Reviews the performance of ViveST using the new Siemens integrase sequencing assay.
Stability of HIV-1 Viral Load From Dried Plasma Using ViveST®, a Novel Dried Plasma Transportation Matrix 24th Clinical Virology Symposium; April 25-29, 2008; Daytona Beach, FL, USA Compares the precision and stability of ViveST vs. fresh-frozen plasma. Five replicates of each sample were stored at different temperatures, measured at 5 points from day 2 through day 56. Two commercial HIV-1 viral load assays used: Roche Amplicor 1.5 and Abbott M2000.
Phenotypic and Genotypic HIV-1 Drug Resistance and Tropism Testing Performed on Plasma Stored in a Dried State 11th European AIDS Conference; October 24-27, 2007; Madrid, Spain Compares ViveST to fresh frozen plasma for viral trophism, phenotypes, and genotypes.
Comparison of Whole Blood, Plasma and PBMC HIV-1 Resistance Genotyping and Matched Dried Samples Using ViveST™, a Novel Dried Transportation Matrix XIV International HIV Drug Resistance Workshop; June 7-11, 2005; Quebec City, Canada Compares fresh-frozen plasma to ViveST plasma; whole blood to ViveST-WB; and PBMC extractions.
Comparison of Hepatitis B Virus INNO-LiPA Genotyping Between Frozen Plasma and ViveST™, a Dried Transportation Matrix 21st Clinical Virology Symposium; May 8-11, 2005; Clearwater Beach, FL, USA Demonstrates the viability of ViveST for HBV utilizing two different extraction methods, then processed on LiPA strips directed at three different areas on the HBV genome. All proved successful.
Successful International Ambient Patient Plasma Transport of HIV-1 Clade A, B and C Using ViveST™, a Novel Dried Transportation Matrix 12th Conference on
Retroviruses and
Opportunistic
Infections; February
22-25, 2005; Boston,
MA, USA
ViveST specimens were prepared and compared to FFP. The comparisons were TRUGENE HIV-1 Genotyping, HIV-1 GeneTanker complete and analyzed with MuTanker software. Samples were shipped from Israel.
Comparison of Viral Load and Resistance Genotyping Between Frozen Plasma and a Novel Dried Plasma Transportation Medium (ViveST™) on Treated Patient Samples XIII International HIV Drug Resistance Workshop; June 8-12, 2004; Tenerife Sur-Costa Adeje, Canary Islands, Spain Demonstrates the viability of ViveST with multiple commercial FDA-approved HIV-1 assays. It also demonstrated excellent results with genotyping both in HIV with TREGENE and hepatitis C.
HIV-1 Load Quantitation: A 17-Year Perspective The Journal of Infectious Diseases, September 2006 Highlights some of the history, accomplishments, and impact of Tom Merigan's laboratory on the use of HIV-1 load as a marker, as well as on updating technologies for determining HIV-1 load, their performance, interpretation of the results, and their use in clinical practice.